Thomas Hollis may refer to:

Thomas Hollis (1659–1731), English merchant, benefactor of Harvard College, donator of the first town bible to Holliston, Massachusetts, which was named for him. Thomas Hollis (1720–1774), English author and political philosopher, also a benefactor of Harvard College. Thomas Brand Hollis (1719–1804), British political radical and dissenter. Tommy Hollis (1954–2001), American actor who played a supporting role in the 1992 film Malcolm X.

See also Hollis Thomas (born 1974), former American football player.