Trials & Tribulations may refer to:

Music Trials & Tribulations (Ace Hood album) or the title song, 2013 Trials & Tribulations (Poetic Hustla'z album) or the title song, 1997 Trials & Tribulations, an album by Bizzy Bone, 2007 "Trials & Tribulations", a song by Polo G from The Goat, 2020

Other uses "Trials and Tribulations" (Fargo), a 2023 TV episode Phoenix Wright: Ace Attorney – Trials and Tribulations, a 2004 visual novel adventure video game

See also Trials and Tribble-ations, a 1996 episode of Star Trek: Deep Space 9