Leona is a feminine given name.

Leona may also refer to:

Places in the United States Leona, Kansas, a city Leona, Texas, a city Leona Creek, a stream in Texas

Arts and entertainment Leona (film), a 2018 Mexican film Leona (instrument), a Mexican stringed instrument "Leona" (song), by Sawyer Brown, 1984 "Leona", a song by Millencolin from Same Old Tunes (Tiny Tunes)

Other uses Leona (skipper), a butterfly genus Leona (sternwheeler), an American steamship in service 1899–1912 319 Leona, an asteroid Rosemary Leona, Vanuatuan businesswoman

See also Jacopo da Leona (died 1277), Italian poet Leona Valley AVA, a wine region in Los Angeles County, California