Sabretooth or sabertooth may refer to:

Animals Saber-toothed cat, several prehistoric felines Smilodon, a prehistoric genus of cat Sabertooth fish, a deep-sea fish found in the tropics Sabre-toothed blenny, Aspidontus taeniatus, a variety of fish that lives deep underwater in the benthic zone Sabertooth blenny, Plagiotremus azaleus, a species of combtooth blenny in coral reefs in the eastern Pacific Ocean Sabertooth salmon, Oncorhynchus rastrosus, an ancient species of salmon Sabretooth tetra, the Payara, Hydrolycus scomberoides, a species of gamefish in the Orinoco River in Venezuela and in the Amazon basin Saber-toothed predator, several distantly related lineages of synapsids Thylacosmilus, a genus of sabre-toothed metatherian predators from the Miocene period Gorgonopsia, an extinct group of sabre-tooth therapsids from the Middle and Late Permian

Sports Sabretooth (mascot), the mascot for the Buffalo Sabres National Hockey League team

Fiction Sabretooth (character), a Marvel Comics supervillain Sabretooth (film), a 2002 made-for-TV movie Sabre-Tooth, a 1966 book by Peter O'Donnell featuring the character Modesty Blaise Captain Sabertooth, a series of stage plays, theatrical films, and a television series by the Norwegian singer and actor Terje Formoe

Other uses SABERTOOTH, a protein sequence and structure alignment algorithm Sabertooth Games, a now defunct Memphis, Tennessee based game company, founded in 2001

See also Sabercat (disambiguation)