Macromphalina floridana is a species of very small sea snail, a marine gastropod mollusk in the family Vanikoridae.

Description The maximum recorded shell length is 3.1 mm.Welch J. J. (2010). "The "Island Rule" and Deep-Sea Gastropods: Re-Examining the Evidence". PLoS ONE 5(1): e8776. .

Habitat The minimum recorded depth for this species is 1 m; maximum recorded depth is 34.5 m.

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