U16 may refer to:

Naval vessels , various vessels , a Black Swan-class sloop of the Royal Navy , a Grimsby-class sloop of the Royal Navy , a submarine of the Austro-Hungarian Navy

Other uses Bugatti U-16, an automobile engine Cubitruncated cuboctahedron Small nucleolar RNA SNORD16 Uint16_t, a 16-bit unsigned integer Uppland Runic Inscription 16 U16, or under-16, is a youth sports category.