Double Six, double six, or double sixes may refer to:

Games Doublesix, a video game company Boxcars (slang), a roll of two dice showing six pips on each die Double six (dominoes), a domino set with a maximum of six pips on each tile end, or the individual domino that has six pips on both ends In pai gow (Chinese dominoes), the Teen tile, a tile with six pips of each color

Music Les Double Six, a French jazz group of the early 1960s Double Six Records, a subsidiary label of Domino Records The Double Six Club, one of the five stages of the Connect Music Festival in Scotland Club Series Double Six, a 12-string guitar made by Burns London

Other Double Six (TV series), 1957 comedy revue on BBC Television Double Six Crash, an airplane crash in 1976 in Malaysia Double Six Monument, a memorial to the airplane crash Double Sixth Festival, traditional Chinese festival Daimler Double-Six, one of two series of automobile engines, or the cars using these engines Schläfli double six, two sets of six lines in space with each line crossing five from the other set Double Six, a race horse that won the Prix de la Salamandre in 1890 Double Sixes, a race horse that was one of the Nellie Morse Stakes top three finishers in 1994 In automatic milking, a possible size of a milking parlor The Double Six Youth Club in Woodseats, Yorkshire, England