Spitz is a German surname. Notable people with the surname include:
Andrés Ojeda Spitz (born 1984), Uruguayan lawyer and politician Armand Spitz (1904–1971), American planetarium designer Bob Spitz, American journalist and author Carl Spitz (1894–1976), Hollywood dog trainer Chantal Spitz (born 1954), French Polynesian writer Dan Spitz (born 1963), American guitarist Dave Spitz (born 1955), American bassist Donald Spitz, American anti-abortion activist Elisa Spitz (born 1963), American figure skater Fannie S. Spitz (1873–1943), American inventor Gerald J. Spitz (1941–2013), American politician Hanneliese Spitz (born 1941), Austrian sprint canoeist Herman H. Spitz (1925–2019), American psychologist Illés Spitz (1902–1961), Hungarian football player and manager Isaac Spitz (1764–1842), Bohemian writer Jacques Spitz (1896–1963), French writer Jason Spitz (born 1982), American football player Leó Szilárd (1898–1964), born Leó Spitz, Hungarian scientist Lewis Spitz (born 1939), South African paediatric surgeon Malte Spitz (born 1984), German politician Marc Spitz (1969–2017), American writer and music journalist Mark Spitz (born 1950), American swimmer René Spitz (1887–1974), Austrian-American psychoanalyst Sabine Spitz (born 1971), German cross-country cyclist Sophie Spitz (1910–1956), American pathologist Tibor Spitz (born 1929), American artist and Holocaust survivor Vivien Spitz (1924–2014), American journalist Werner Spitz (1926–2024), German forensic pathologist Yom-Tob Spitz (1797–1874), Bohemian writer
Fictional characters Adam Spitz, Sharon Spitz, Josh Spitz, and Helen Spitz, four characters in the television series Braceface