William Barker may refer to:
Politicians William Barker (translator) ( 1570), English translator and MP for Great Yarmouth and Bramber William Barker (MP for Berkshire) (died 1685), English Member of Parliament for Berkshire Sir William Barker, 5th Baronet (1685–1731), British Member of Parliament for Ipswich, Thetford and Suffolk William Barker (Queensland politician) (1819–1886), member of the Queensland Legislative Council William F. Barker (1823–1895), American merchant and politician William J. Barker (Denver mayor) (1832–1900), American politician
Judges William J. Barker (1886–1968), American lawyer and judge William M. Barker (1941–2023), Chief Justice of the Tennessee Supreme Court from 1995 to 2009
Sportspeople William Barker (Surrey cricketer) (1857–?), English cricketer William Barker (tennis) (born 1981), British tennis player Billy Barker (footballer, born 1883) (1883–1937), footballer for Middlesbrough F.C. in the early 20th century; see List of Middlesbrough F.C. players Bill Barker (footballer) (1924–2002), footballer who played for Stoke City Will Barker (American football) (born 1987), American football player
Religion William Barker (priest, died 1776), Irish priest, Dean of Raphoe William Barker (priest, died 1917) (1838–1917), Dean of Carlisle William Morris Barker (1854–1901), American bishop of the Episcopal Diocese of Olympia
Others William Barker (chemist) (1810–1873), Irish professor of chemistry William Barker (prospector) (1817–1894), English miner and prospector who found gold in Canada William Burckhardt Barker (1810–1856), English orientalist William George Barker (1894–1930), Canadian Victoria Cross recipient and World War I flying ace William Gibbs Barker ( 1811–1897), English clergyman and genealogist William Higgs Barker (1744–1815), English Hebraist William Robert Barker, Australian botanist William S. Barker (born 1934), American church historian, educator, and leader Will Barker (director) (1867–1951), aka William George Barker, English film producer and director Bill Barker (born 1957), creator of Schwa, underground conceptual artwork Bill Barker, police officer who died in the November 2009 Great Britain and Ireland floods, namesake of Barker Crossing Bill Barker, actor who portrayed Dr. Duckbill Platypus and Elsie Jean Platypus on Mister Rogers' Neighborhood