Lythgoe is a surname. Notable people with the surname include:
Albert Lythgoe (1868–1934), archaeologist and curator of the Metropolitan Museum of Art Alf Lythgoe (1907–1967), British footballer Bonnie Lythgoe (born c. 1950), British dancer and theatre producer & director Clive Lythgoe (1927–2006), British musician David Lythgoe (born c. 1880), American actor Ian G. Lythgoe (1914–2000), New Zealand accountant and public administrator Nigel Lythgoe (born 1949), British dancer, director & producer Simon Lythgoe (born late 20th century), British-born film technician and producer
See also Mary Lythgoe Bradford (1930-2022), American writer Lithgow (surname)