Ome or OME may refer to:
Places Ome (Bora Bora), a public island in the lagoon of Bora Bora Ome, Lombardy, Italy, a town and comune in the Province of Brescia Ōme, Tokyo, a city in the Prefecture of Tokyo Ome (crater), a crater on Mars
Transportation Ōme Line, a railway in the Prefecture of Tokyo Ōme Station, a railway station in Ōme Ōme (train), an express train on the Ōme Line OME, the IATA and FAA code for Nome Airport, Alaska
Acronym Office of Manpower Economics, a body of the United Kingdom government Ontario Ministry of Education, Canada Open Microscopy Environment Osaka Mercantile Exchange Otitis media with effusion, the accumulation of fluid in the middle ear -ome, a suffix in biology and related sciences, associated with omics
People Open Mike Eagle, a rapper from Los Angeles, California Jaslyn Ome, Playboy Playmate of the Month for April 2013
Chemicals Polyoxymethylene dimethyl ethers Often abbreviated as OME3, OME4, OME5, and "OMEx" in papers where it is discussed as a Second-generation biofuel / Electrofuel See also Ōme Kaidō, a main road running through the city of Ōme OME-B, OME-C, OME-E and OME-Ant, parts of the MINERVA spacecraft