TPY may refer to:
First-pass yield, also known as throughput yield tons per year, a measure of mass over time TPY-2, a type of long-range radar TPY-4, a type of long-range radar tpy, the ISO code for the Trumai language TPy, a proposed variant of Py (cipher) TPY, the IATA code for Torino Porta Nuova railway station in Turin, Italy tpy, abbreviation for the chemical ligand terpyridine