This is intended to be a complete list of the Pennsylvania state historical markers in Philadelphia County, as placed by the Pennsylvania Historical and Museum Commission (PHMC) in the U.S. state of Pennsylvania.

As of 2021, there were 321 combined Roadside (larger) and City (narrower) markers affixed on posts and Plaque markers affixed to buildings or structures in Philadelphia County, Pennsylvania, which is coterminous with the city of Philadelphia. Of these, 12 are listed as Missing. Latitude and longitude coordinates are given as provided by the PHMC's database.

Historical markers Marker title ImageDate dedicatedLocationMarker typeTopicsNeighborhoodNotes A.M.E. Book Concern631 Pine St., PhiladelphiaCityAfrican American, ReligionSociety HillAcademy of Natural Sciences302 Market St., PhiladelphiaCityEducation, Science and MedicineOld CityAfrican American Baseball in PhiladelphiaSW corner, Belmont and Parkside Aves., PhiladelphiaRoadsideAfrican American, Baseball, Sports and RecreationFairmount Park (Parkside)African Zoar Methodist Episcopal Church401 Brown St. (at N 4th), PhiladelphiaCityAfrican American, Religion, Underground RailroadNorth Philadelphia East (Northern Liberties)Alain Leroy Locke (1886-1954)2221 S 5th St., PhiladelphiaCityAfrican American, Education, Professions and Vocations, WritersSouth Philadelphia (Whitman) MissingAlbert M. Greenfield (1887-1967)1315 Walnut St., PhiladelphiaCityAfrican American, Business and Industry, Government and Politics 20th Century, ReligionWashington Square WestAlfred J. Reach (1840-1928)1820 Chestnut St., PhiladelphiaCityBaseball, Sports and RecreationRittenhouse SquareAmerica's First Lager905 N American St., PhiladelphiaCityBusiness and IndustryNorth Philadelphia East (Northern Liberties)American Bandstand4601 Market St., PhiladelphiaRoadsideBusiness and Industry, Motion Pictures and TelevisionWest Philadelphia (Walnut Hill)American Friends Service Committee1501 Cherry St., at Friends Ctr., PhiladelphiaCityReligionLogan Square (Hahnemann)American Pharmaceutical AssociationNW corner, Market and N 7th sts., PhiladelphiaCityScience and Medicine, Professions and Vocations