ICER may refer to:

ICER (file format), a wavelet-based image compression file format used by the NASA Mars Rovers Icer, a character in the Masters of the Universe franchise Institute for Clinical and Economic Review, a Boston-based nonprofit organization seeking to improve healthcare Incremental cost-effectiveness ratio International Computing Education Research, an annual research workshop sponsored by SIGCSE

See also Icer Air, stylized as ICER AIR, an urban big-air ski and snowboard event held in San Francisco from 2005 through 2008