The 2010 Atlanta Tennis Championships – Singles was part of the 2010 ATP World Tour. Defending champion Robby Ginepri lost in the second round to fellow American and eventual champion Mardy Fish. Fish went on to win his second title of the year—and of the month—by defeating compatriot John Isner in the final, 4–6, 6–4, 7–6(7–4).

Seeds The top four seeds receive a bye into the second round.

Draw

Finals

Top half

Bottom half

References Main draw Qualifying Singles draw