Paul-Henri Mathieu was the defending champion but lost in the first round to Rainer Schüttler.
Schüttler won in the final 7–5, 6–3 against Arnaud Clément.
Seeds
Rainer Schüttler (champion) Sébastien Grosjean (first round) Paradorn Srichaphan (semifinals) Félix Mantilla (first round) Mardy Fish (first round) Wayne Ferreira (first round) Marat Safin (first round) Yevgeny Kafelnikov (first round)
Draw
Finals
Top half
Bottom half
References 2003 Grand Prix de Tennis de Lyon Main Draw 2003 Grand Prix de Tennis de Lyon Qualifying Draw