Penmetsa (Telugu: పెన్మత్స), Penumatsa, Penmatsa or Penmethsa is a Telugu Raju surname. Notable people with the surname include:
Penmetsa Ram Gopal Varma, Indian film director and producer Penmetsa Satyanarayana Raju, Supreme Court Chief Justice of India Penmetsa Subbaraju, Indian actor Penmetsa Venkata Ramaraju, Indian music composer Penmetsa Surapa Raju, Ancestor to all Penmetsa's