Wiley House may refer to:

(by state then town) Emily Wiley House, a historic house in Washington, D.C. Orton H. Wiley House, a historic house in Nampa, Idaho, listed on the NRHP in Canyon County Tobe Wiley House, Paintsville, Kentucky, listed on the NRHP in Johnson County James Sullivan Wiley House, a historic house in Dover-Foxcroft, Maine Benjamin Wiley House, a historic house in North Fryeburg, Maine Wiley-Ringland House, a historic house in Chevy Chase, Maryland Caleb Wiley House, a historic house in Stoneham, Massachusetts Mason-Lloyd-Wiley House, a historic house in Chapel Hill, North Carolina, home of Thomas F. Lloyd KidsPeace, a Pennsylvania-based children's charity, formerly known as Wiley House Wiley-Cloud House, a historic house in Kennett Township, Pennsylvania, listed on the NRHP in Chester County Thomas W. Wiley House, a historic house in McKinney, Texas, listed on the NRHP in Collin County

See also Wylie House, a historic house in Bloomington, Indiana