James Paine may refer to:
James Paine (architect) (1717–1789), English architect James Paine (rower), English rower James Paine (sculptor) (1745–1829), English sculptor and architect James Carriger Paine (1924–2010), American judge
See also James Pain (1779–1877), English architect James Payn (1830–1898), English novelist James Payne (disambiguation) Paine (surname)