The Michaelis–Becker reaction is the reaction of a hydrogen (thio)phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl (thio)phosphonate. Yields of this reaction are often lower than the corresponding Michaelis–Arbuzov reaction.Fletcher, M.D. Organophosphorus Reagents; Murphy, P.J. Ed.; University Press: Oxford, 2002; pp. 185.
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