E35 may refer to:

Roads European route E35 Guthrie Corridor Expressway, route E35 in Malaysia Nishi-Kyūshū Expressway, route E35 in Japan Ecuador Highway 35, signposted as E-35.

Vehicles HMS E35, a British E class submarine built in 1916 VinFast VF e35, a 2022–present Vietnamese compact electric SUV