Hoofddorppleinbuurt () is a neighborhood of Amsterdam, Netherlands, part of the borough of Amsterdam-Zuid. The district had 10,771 inhabitants as of 1 January 2005.Gemeente Amsterdam, Gebiedsindeling 2005, V44 The total area is 96.71 hectares.

Hoofddorppleinbuurt was built in the 1920s. Since 1927 the neighborhood through the Zeilbrug has been connected to Amstelveenseweg. It is a mostly a residential neighborhood, but there are a few companies and other institutions.

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