Betto is a surname. Notable people with the surname include:

Alice Betto (born 1987), Italian triathlete Frei Betto (born 1944), Brazilian writer and theologist Kaoru Betto (1920–1999), Japanese baseball player

See also Blessed Betto (sixth century), father of St. Lupus of Sens Callie Betto (Dryad), a mutant character in Marvel Comics