R. Hanina (or Hananiah) of Sepphoris (, read as Rabbi Hananiah DeTziporin; alternative Hebrew spelling: Hiddushei haRashba to Sanhedrin 105a) sometimes cited merely as R. Hanina [Hananiah] or Hanina (Hananiah) II, was an Amora of the Land of Israel (in Byzantine Galilee at the time), of the fifth generation of the Amora era.

Biography He was a disciple of Rabbi Mani II.Yerushalmi Pesachim 1 27d; Yerushalmi Moed Kattan 3 82c He gradually rose to his master's level and discussed with him as a "fellow student" many halakhic questions.Yerushalmi Sanhedrin 2 19d; Yerushalmi Shevuot 6 37b Eventually he moved to Sepphoris, where he became the religious head of the community; hence he is sometimes cited as Hanina of Sepphoris.Yerushalmi Nedarim 9 41b When Mani also moved to Sepphoris (due to Roman persecutions in Tiberias), Hanina resigned the leadership in his favor—an act of self-abnegation extolled by the Rabbis as having few parallels.Yerushalmi Pesachim 6 33aMANI, Jewish Virtual Library; Article Hanina, however, did not long remain in Palestine. As the persecutions became general and intolerable, he emigrated to Babylonia, where Ashi frequently sought information from him.Bava Batra 25b; Hullin 139b Hanina's family accompanied him, and were highly respected in their adopted country. There Hanina's daughter married the son of Ravina.Niddah 66b

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