Sandifer is a surname. Notable people with the surname include:
Bill Sandifer (born 1952), American football player Cecil T. Sandifer (1923–2022), American politician and funeral director Dan Sandifer (1927–1987), American football player Phillip Sandifer (born 1959), American writer, recording artist and producer Robert Sandifer (1983–1994), American murder victim
See also Sandifer syndrome