Zappalà or Zappala is a surname. Notable people with the surname include:
Frank J. Zappala (1898–1988), American politician and lawyer Gregorio Zappalà (1833–1908), Italian sculptor Stefano Zappalà (1941–2018), Italian politician and Member of the European Parliament for Central with the Forza Italia Stephen Zappala, American Democratic politician and attorney who is the District Attorney of Allegheny County, Pennsylvania Stephen Zappala Sr. (1932–2021), American lawyer and former Pennsylvania Supreme Court Chief Justice Vincenzo Zappalà (born 1945), Italian astronomer
See also 2813 Zappalà, main belt asteroid with an orbital period of 2030 Zapala