Trinkle is a surname. Notable people with the surname include:
Elbert Lee Trinkle (1876–1939), American politician and 49th Governor of Virginia Jeff Trinkle, American computer scientist Ken Trinkle (1919–1976), American baseball player
See also Trinkle Mansion, a historic building in Wytheville, Virginia, United States 24204 Trinkle, a main-belt asteroid