Šimek (feminine: Šimková) is a Czech, Slovak and Croatian surname. It is derived from the given name Šimon, a variant of Simon. The name also appears in the Anglicized form as Shimek and Simek, and in the Germanized form as Schimek. Notable people with the surname include:

David Šimek (born 1998), Czech footballer Juraj Šimek (born 1987), Slovak-born Swiss ice hockey player Karlo Šimek (born 1988), Croatian footballer Miloslav Šimek (1940–2004), Czech comedian Miroslav Šimek (born 1959), Czech slalom canoer Radim Šimek (born 1992), Czech ice hockey player

See also 14098 Šimek, an asteroid