Purifoy may refer to:
13063 Purifoy, a minor planet designation
People with the name Purifoy Bill Purifoy (1959–2013), American football defensive end in the United States Football League John Purifoy (1842–1927) American politician from Alabama Loucheiz Purifoy (born 1992), American professional football defensive back in the Canadian Football League Noah Purifoy (1917–2004), American visual artist Tiara Purifoy, contestant on the TV series American Idol season 3 Tristan Purifoy (born 1990), American football wide receiver in the National Arena League
Others Jake Purifoy, fictional character in The Southern Vampire Mysteries book series and TV series