Pizzarello is:
- an Italian traditional food from Puglia, a region in the southern part of Italy. It is called Pizzarello or "Pizzaridd" in the southern dialect;
- an Italian surname. Notable people with the surname include:
Alberto Pizzarello, Gibraltarian poet Sandra Pizzarello (1933–2021), Italian biochemist
See also Asteroid 7377 Pizzarello, named after Sandra Pizzarello Pizzarelli