Pattillo is a surname. Notable people with the surname include:

Alan Pattillo (1929–2020), British writer and director Charles C. Pattillo (1924–2019), American Air Force lieutenant general Cuthbert A. Pattillo (1924–2014), United States Air Force Major General Greg Pattillo (born 1977), American beatboxing flautist Johnny Pattillo (1914–2002), Scottish football player and manager Marcus Pattillo (born 1977), American former Major League Baseball umpire Mary Pattillo, American sociologist and African-American Studies scholar Melba Pattillo Beals, American school de-segregator (Little Rock Nine). Roland Pattillo, African-American medical doctor and researcher

See also Meanings of minor planet names: 58001–59000#535