McKeegan is an Irish surname. Notable people with the surname include:
Karl McKeegan (born 1978), Northern Irish hurler Leonard McKeegan (born 1963), Irish hurler Michael McKeegan (born 1971), Northern Irish musician Tim McKeegan (1877–1939), Australian rules footballer Trent McKeegan (born 2000), Irish cricketer
See also 5663 McKeegan, a main-belt asteroid