Masayo (written: 雅世 or 雅代, 政代, 正世, 正代 or 匡代) is a feminine Japanese given name. Notable people with the name include:

, Japanese swimmer , Japanese voice actress , Japanese synchronized swimmer and coach , Japanese entomologist , Japanese voice actress , Japanese diver , Japanese physician, ophthalmologist and stem cell researcher , Japanese politician

See also 5295 Masayo, a main-belt asteroid