Mannucci is an Italian surname. Notable people with the surname include:
Lucia Mannucci (1920–2012), Italian singer Filippo Mannucci (born 1974), Italian rower Gaspare Mannucci (1575–1642), Italian Baroque painter Paolo Mannucci (born 1942), Italian cyclist
See also Carlos A. Mannucci, a Peruvian football club 2219 Mannucci, a main-belt asteroid
See also Manucci