Giorgini is an Italian surname, derived from Giorgio (George). Notable people with the surname include:
Aldo Giorgini (1934–1994), Italian artist Daniele Giorgini (born 1984), Italian tennis player Frank Giorgini, American ceramist Mass Giorgini (born 1968), American musician and record producer Saskia Giorgini, Italian-Dutch pianist
See also 6775 Giorgini, a main-belt asteroid