Defi may refer to:
DéFI (Démocrate fédéraliste indépendant), a political party in Belgium Defi language Défi sportif, disabled multisport event Le Défi, a defunct America's Cup syndicate from France Le Défi Media Group, mass media company in Mauritius 10332 Défi, a main belt asteroid discovered in 1991 Decentralized finance, a form of finance based on cryptocurrencies
See also Defy (disambiguation)