Calandrelli is a surname. Notable people with the surname include:

Alexander Calandrelli (1834–1903), German sculptor of Italian descent Andrew Calandrelli, American mixed martial artist Emily Calandrelli, American science communicator Giuseppe Calandrelli (1749–1827), Italian priest and astronomer Ignazio Calandrelli (1792–1866), Italian priest and astronomer (nephew of Giuseppe) Jorge Calandrelli (1939–2026), Argentine composer, arranger and conductor Susana Calandrelli (1901–1978), Argentine writer and teacher