Affliction or Afflicted may refer to:
Books Affliction (novel), a 2013 Anita Blake: Vampire Hunter novel by Laurell K. Hamilton Affliction, a novel by Russell Banks, basis of the 1998 film
Film and TV Affliction (1997 film), a 1997 American drama by Paul Schrader Affliction (1996 film), a 1996 American documentary film Affliction (2021 film), a 2021 Indonesian horror film "Affliction" (Star Trek: Enterprise), an episode of Star Trek: Enterprise Afflictions: Culture & Mental Illness in Indonesia, a 2010–2011 ethnographic documentary film series The Afflicted (film), a 2011 American horror film by Jason Stoddard Afflicted (film), a 2013 Canadian horror film by Derek Lee and Clif Prowse Afflicted (TV series), a 2018 Netflix documentary series
Brands Affliction Clothing, an American clothing manufacturer and retailer Affliction Entertainment, a defunct mixed martial arts promotion company created by Affliction Clothing
Music Afflicted (band), a Swedish technical death metal band Affliction (album), a 1996 album by Econoline Crush
See also Disease Suffering