Old Central High School may refer to:

Old Central High School (Pittsfield, Massachusetts), listed on the National Register of Historic Places in Berkshire County, Massachusetts Old Central High School (Kalamazoo, Michigan), listed on the National Register of Historic Places in Kalamazoo County, Michigan Central High School (Shreveport, Louisiana), also known as Old Central High School (Shreveport, Louisiana), listed on the National Register of Historic Places in Caddo Parish