Newcomb House may refer to:

in the United States (by state then city) Newcomb House (Pasadena, California), listed on the National Register of Historic Places (NRHP) in Los Angeles County Richard F. Newcomb House, Quincy, Illinois, listed on the National Register of Historic Places listings in Adams County Newcomb Place, Quincy, Massachusetts, listed on the NRHP in Norfolk County John Newcomb House, Wellfleet, Massachusetts, listed on the NRHP in Barnstable County Newcomb House (Carthage, Missouri) Van Horn–Newcomb House, Englewood, New Jersey, listed on the NRHP in Bergen County Newcomb-Brown Estate, Pleasant Valley, New York, listed on the NRHP in Dutchess County