RKO refers to RKO Pictures, an American film company.
RKO may also refer to:
Organisations RKO General, holding company for General Tire and Rubber Company up to 1981 RKO Radio Network, a subsidiary of RKO General Rutten Komt Op, a football team of Rutten, Flevoland
Other Reichskommissariat Ostland, Nazi-controlled Baltic territory in WWII Randal Keith Orton or Randy Orton, a professional wrestler signed to WWE his finishing move, the RKO, a jumping cutter Rated-RKO, his former wrestling team