Locke House may refer to:
in the United States (by state then city) Esther Locke House, Hardy, Arkansas, listed on the National Register of Historic Places (NRHP) in Sharp County Locke-Nall House, Lockesburg, Arkansas, listed on the NRHP in Sevier County Locke House and Barn, Lockeford, California, listed on the NRHP in San Joaquin County Locke House (Oakland, California), listed on the National Register of Historic Places in Alameda County Locke-Mount House, Goshen, Kentucky, listed on the NRHP in Oldham County Capt. Benjamin Locke House, Arlington, Massachusetts, listed on the NRHP Charles Adams-Woodbury Locke House, Somerville, Massachusetts, listed on the NRHP in Middlesex County Locke-Baldwin-Kinsley House, Stoneham, Massachusetts, listed on the NRHP Asa Locke House, Winchester, Massachusetts, listed on the NRHP Capt. Josiah Locke House, Winchester, Massachusetts, listed on the NRHP Philemon Wright/Asa Locke Farm, Winchester, Massachusetts, listed on the NRHP Elijah Locke House, Rye, New Hampshire, listed on the NRHP in Rockingham County Hadley-Locke House, Corvallis, Oregon, listed on the NRHP in Benton County Locke House (Decatur, Tennessee), formerly listed on the National Register of Historic Places in Meigs County