State Office Building may refer to:
State Office Building (Denver, Colorado), in Civic Center Historic District (Denver, Colorado) (or Denver Civic Center) State Office Building (Lansing, Michigan), listed on the National Register of Historic Places in Ingham County, Michigan Alfred E. Smith Building (formerly the State Office Building), in Albany, New York State Office Building (Binghamton, New York), infamous for a 1981 fire where a transformer explosion contaminated the building with PCBs, leading to a 13-year cleanup effort Pittsburgh State Office Building, in Pittsburgh, Pennsylvania State Office Building (Madison, Wisconsin), listed on the National Register of Historic Places in Dane County, Wisconsin State Office Block, Sydney, former Government Offices in New South Wales
See also State Tower Building, a 1928 high-rise building located in Syracuse, New York