Hymie may refer to:
Hymie Buller (1926–1968), Canadian-born US All-Star NHL hockey player Hymie Gill (born 1973), New Zealand retired field hockey player Hymie Kloner (born 1929), South African former footballer Hymie Shertzer (1909–1977), American jazz saxophonist Hymie Weiss (1898–1926), Polish-American gangster rival of Al Capone Hymie Simon (1913–2011), American comic book writer Hymie, a recurring character on the television show Get Smart A religious slur applied to Jews
See also Hyman Martin (1903 –1987), also known as "Pittsburgh Hymie", a mobster Hyman Holtz (c. 1896 – 1939?), "Little Hymie", New York racketeer Jamie Hyman