Guazzo is a surname. Notable people with the surname include:
Francesco Maria Guazzo (c. 1570 – c. 1630), teacher of theology and author of the witch-finders’ manual Compendium Maleficarum Marco Guazzo (died 1566), Italian writer from Padua Stefano Guazzo (1530–1593), Italian writer from Casale Monferrato
See also
Guazzo, the Italian term for gouache Guazzoni