Great Red Dragon may refer to:

A character in the Book of Revelation The Great Red Dragon paintings, a series of paintings by William Blake Great Red Dragon, an alter ego of the fictional character Francis Dolarhyde in the novel Red Dragon by Thomas Harris Great Red Dragon, a fictional character in the comic book series Bone "The Great Red Dragon", an episode of the television series Hannibal "The Great Red Dragon", an episode of the television series The Mentalist

See also Red dragon (disambiguation)