The 1999 Copa Bolivia was the fourth edition of the Copa Bolivia. Jorge Wilstermann were the defending champions after beating Blooming 2–1 on aggregate in the previous season's final. The format of the tournament had change as it became knockout only.
First round
Second round
Third round Including the four best losers from the second round.
Fourth round
Quarter-final Including the two best losers from the fourth round.
Semi-final
Final
References