DE.15, DE-15, DE 15, DE15 or variant, may refer to:

DE-15, a D-subminiature connector type VGA connector, the common application of the DE-15 connector DE.15, a Nickel–Strunz classification

Delaware Route 15 DE 15, one of the postcodes for Burton upon Trent DE15, an OECD region, see List of OECD regions by GDP (PPP) per capita JNR Class DE15, a Japanese diesel locomotive type

See also DD-15 (disambiguation)