Masemola is a Northern Sotho surname. People with this surname include: Fannie Masemola (b. 1964), South African police official Manche Masemola (1913–1928), South African Christian martyr Jafta Masemola (1929–1990), South African anti-apartheid activist Richard Masemola (), South African Anglican priest
See also Ga Masemola, village in Limpopo Province, South Africa