Grushin (masculine, ) or Grushina (feminine, ) is a surname of Russian origin. It is derived from the sobriquet "груша" ("pear"). Notable people with the surname include:
Aleksandr Grushin (born 1984), Russian footballer Andrey Grushin (born 1988), Russian footballer Boris Grushin (1929–2007), Russian Soviet philosopher, sociologist and scientist Elena Grushina (born 1975), Ukrainian ice dancer Olga Grushin (born 1971), Russian-American novelist Pyotr Grushin (1906–1993), Russian Soviet rocket scientist